I-59 Hotels in Mississippi

I-59 Road Trip Hotels In Mississippi Cities and Towns

Meridian to Laurel: 58 miles

Laurel to Hattiesburg: 30 miles

Home of the University of Southern Mississippi

Hattiesburg to Picayune: 61 miles

Hampton Inn on the southern end of the Birmingham metro area gets great reviews

Save space and keep things organized when traveling #ad

A place to stay on one of those long road trips on I-5 through California

Hotel is on the north side of Pell City, at the town's exit off I-20 in eastern Alabama

Hotel on I-10 in New Mexico, on the long ride from Texas to the Pacific Coast

Just the right size to get you through the TSA checkpoint without a hassle #ad

Comfortable road trip hotel adjacent to I-95 in southern Virginia