Road Trip on I-70: St. Louis to Baltimore
Distance: 826 miles
Road Trip Hotels Between St. Louis, MO and Baltimore, MD
How many miles per day?
To help with planning your trip, we mark suggested places for an overnight stay if you're comfortable driving 300 miles per day or 400 miles per day. At around 300 miles per day, it will take you 2 - 3 days to make the trip from St. Louis to Baltimore. If you're okay with driving 400 miles per day the trip should take 2 to 3 days.Plan your return road trip from Baltimore to St. Louis
St. Louis, MO Hotels
I-70 cross the Mississippi River into central St. Louis and then goes around the north side
Distance to Baltimore: 826 miles
St. Louis to Greenville: 50 miles
Greenville, IL Hotels
Distance from St. Louis: 50 miles
Distance to Baltimore: 776 miles
Greenville to Vandalia: 16 miles
Vandalia, IL Hotels
Distance from St. Louis: 66 miles
Distance to Baltimore: 760 miles
Vandalia to Effingham: 34 miles
Effingham, IL Hotels
Distance from St. Louis: 100 miles
Distance to Baltimore: 726 miles
Effingham to Casey: 35 miles
Casey, IL Hotels
Distance from St. Louis: 135 miles
Distance to Baltimore: 691 miles
Casey to Terre Haute: 33 miles
Terre Haute, IN Hotels
Distance from St. Louis: 168 miles
Distance to Baltimore: 658 miles
Terre Haute to Cloverdale: 34 miles
Cloverdale, IN Hotels
Distance from St. Louis: 202 miles
Distance to Baltimore: 624 miles
Cloverdale to Indianapolis: 41 miles
Indianapolis, IN Hotels
I-70 rolls through the center of Indianapolis on the east side of downtown
Distance from St. Louis: 243 miles
Distance to Baltimore: 583 miles
Indianapolis to Greenfield: 22 miles
Greenfield, IN Hotels
Distance from St. Louis: 265 miles
Distance to Baltimore: 561 miles
Greenfield to Richmond: 53 miles
Richmond, IN Hotels
Small city at the Indiana-Ohio border
Distance from St. Louis: 318 miles
Distance to Baltimore: 508 miles
Richmond to Brookville: 22 miles
Brookville, OH Hotels
Distance from St. Louis: 340 miles
Distance to Baltimore: 486 miles
Brookville to Dayton: 16 miles
Dayton, OH Hotels
I-70 goes through the Dayton area on the north side of the city
Distance from St. Louis: 356 miles
Distance to Baltimore: 470 miles
Dayton to Springfield: 18 miles
Springfield, OH Hotels
Distance from St. Louis: 374 miles
Distance to Baltimore: 452 miles
Springfield to Columbus: 45 miles
Columbus, OH Hotels
I-70 passes through Columbus on the south side of downtown
Distance from St. Louis: 419 miles
Distance to Baltimore: 407 miles
Columbus to Zanesville: 56 miles
Zanesville, OH Hotels
Distance from St. Louis: 475 miles
Distance to Baltimore: 351 miles
Zanesville to Cambridge: 24 miles
Cambridge, OH Hotels
Distance from St. Louis: 499 miles
Distance to Baltimore: 327 miles
Cambridge to St. Clairsville: 39 miles
St. Clairsville, OH Hotels
Distance from St. Louis: 538 miles
Distance to Baltimore: 288 miles
St. Clairsville to Wheeling: 8 miles
Wheeling, WV Hotels
I-70 crosses the Ohio River into Ohio in Wheeling
Distance from St. Louis: 546 miles
Distance to Baltimore: 280 miles
Wheeling to Triadelphia: 9 miles
Triadelphia, WV Hotels
Distance from St. Louis: 555 miles
Distance to Baltimore: 271 miles
Triadelphia to Washington: 23 miles
Washington, PA Hotels
Distance from St. Louis: 578 miles
Distance to Baltimore: 248 miles
Washington to Bentleyville: 15 miles
Bentleyville, PA Hotels
Distance from St. Louis: 593 miles
Distance to Baltimore: 233 miles
Bentleyville to Belle Vernon: 10 miles
Belle Vernon, PA Hotels
Distance from St. Louis: 603 miles
Distance to Baltimore: 223 miles
Belle Vernon to New Stanton: 14 miles
New Stanton, PA Hotels
Distance from St. Louis: 617 miles
Distance to Baltimore: 209 miles
New Stanton to Donegal: 18 miles
Donegal, PA Hotels
Distance from St. Louis: 635 miles
Distance to Baltimore: 191 miles
Donegal to Somerset: 21 miles
Somerset, PA Hotels
Distance from St. Louis: 656 miles
Distance to Baltimore: 170 miles
Somerset to Bedford: 36 miles
Bedford, PA Hotels
Distance from St. Louis: 692 miles
Distance to Baltimore: 134 miles
Bedford to Breezewood: 18 miles
Breezewood, PA Hotels
Distance from St. Louis: 710 miles
Distance to Baltimore: 116 miles
Breezewood to Hagerstown: 52 miles
Hagerstown, MD Hotels
Distance from St. Louis: 762 miles
Distance to Baltimore: 64 miles
Hagerstown to Frederick: 23 miles
Frederick, MD Hotels
Distance from St. Louis: 785 miles
Distance to Baltimore: 41 miles
Frederick to Baltimore: 41 miles
Baltimore, MD Hotels
The eastern terminus of I-70 is at the junction with I-695 on the west side of Baltimore
Distance from St. Louis: 826 miles
Recent Updates
Hampton Inn & Suites Bessemer Birmingham
Hampton Inn on the southern end of the Birmingham metro area gets great reviews
BAGSMART Toiletry Travel Bag
The easy way to keep your toiletries organized when traveling - in 12 different colors! #ad
Holiday Inn Express Westley
A place to stay on one of those long road trips on I-5 through California
Holiday Inn Express Hotel & Suites Pell City
Hotel is on the north side of Pell City, at the town's exit off I-20 in eastern Alabama
Holiday Inn Express & Suites Willcox
Hotel on I-10 in New Mexico, on the long ride from Texas to the Pacific Coast
Mrsdry Travel Bottles for Toiletries
Just the right size to get you through the TSA checkpoint without a hassle #ad
Fairfield Inn & Suites by Marriott Stony Creek
Comfortable road trip hotel adjacent to I-95 in southern Virginia